Natasha Leggero Thanks Bottleworks Hotel, Warns Fans of Poison Oak

Comedian shares snaps from Indianapolis weekend stay and playfully flags an itchy memento.

By Reshmi Das

Thank You Indianapolis

Natasha Leggero touched down in Indianapolis over the weekend for two sold-out shows at Helium Comedy Club. Once her punchlines had landed, the comedian checked in with Instagram followers from the heart of the Bottleworks District. “Thank you Indianapolis and the gorgeous @bottleworks_weddings hotel for hosting me this weekend while I was at @heliumcomedyind! Zoom in for poison oak,” she captioned a series of lobby-and-lounge selfies.

Zooming In For Poison Oak

In the images, Leggero poses effortlessly against the hotel’s vibrant tilework, wearing a cozy robe and oversized shades. What first looked like a styling flourish turned out to be something less glamorous: a red, blistered rash creeping up her forearm. Fans quickly spotted it and applauded her for the frank disclaimer. The comedian later confirmed that she’d picked up a dose of poison oak while exploring nearby canal-side trails between her sets.

Natasha Leggero Thanks Bottleworks Hotel, Warns Fans of Poison Oak pinit button
Image: Instagram

“I guess Indiana flora wanted to test my immunity,” Leggero quipped in a follow-up story, rubbing in the lesson: if you’re wandering the green spaces around the restored bottling plant, keep an eye on what you brush against.

Natasha Leggero Thanks Bottleworks Hotel, Warns Fans of Poison Oak pinit button
Image: Instagram

A Night At Helium Comedy Club

Helium Comedy Club, part of a national chain of stand-up venues, welcomed Leggero for back-to-back performances on Friday and Saturday. Known for her razor-sharp social commentary—whether riffing on modern marriage in her Netflix special The Honeymoon Standup Special or skewering high-society tropes on Comedy Central’s Another Period—she had the room roaring from the first joke. Reviews noted her perfect timing and knack for turning personal mishaps into comic gold.

Natasha Leggero Thanks Bottleworks Hotel, Warns Fans of Poison Oak pinit button
Image: Instagram

Helium’s general manager, Mark Hall, praised her energy: “Natasha came in ready to work, and she left the crowd wanting more. It’s always a treat when a performer interacts so genuinely with a new city.”

Bottleworks Hotel Backstory

The Bottleworks Hotel sits at the center of Indianapolis’s revitalized Mass Ave district. Housed in a 1910 Coca-Cola bottling plant, the boutique property is celebrated for its industrial-chic design, rooftop bar, and easy access to the Indiana Convention Center. Leggero’s shout-out highlights how the space has become a go-to destination for touring performers.

Next Stop: Newport Comedy Fest

Leggero and her husband, comedian Moshe Kasher, have been on a non-stop travel circuit this spring. Earlier this month she headlined the Rogue Island Comedy Festival in Newport, Rhode Island, drawing thousands for a one-off show at the Jane Pickens Theater on May 24. Photos shared by promoter @rogueislandcomedy captured her in full command of the stage, riffing on everything from coastal weather to festival crowds.

The couple also co-hosts The Endless Honeymoon Podcast, which embarks on a summer tour with stops in Portland, Seattle, and Los Angeles. That lineup was announced via Instagram last week, teasing a roster of celebrity guests and interactive segments for live audiences.

Leggero’s calendar is filling fast: she’s slated to appear in a recurring role on the upcoming second season of Poker Face and has her own stand-up special in post-production for streaming. Her blend of self-deprecation and biting social satire continues to resonate whether she’s on TV, a podcast stage, or in the lobby of a century-old bottling plant.

As for the rash? She’s treating it with over-the-counter ointments and a hearty dose of humor. “I’ll survive,” she assured followers, “but I’ll think twice before hugging any more foliage.”

Natasha Leggero’s Indianapolis stop was equal parts comedy and cautionary tale, confirming that even the sharpest wit can’t outsmart nature’s hidden surprises.

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Reshmi Das has over four years of experience as a content writer, covering parenting and films. She writes for Hollywoodjunction and Momjunction. Her interest in journaling and writing made this biotechnology postgraduate to take up content as her full-time profession.

Read full bio of Reshmi Das
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